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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-29a
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples, retinas; RB cell lines Y79 and SO-RB50
Methods transfection, qRT‑PCR, MTT assay, cell cycle and apoptosis assay, transwell assay, luciferase reporter assay, Western blot, xenograft
Expression pattern down-regulated
Functional description miR-29a exerts a tumor suppressor effect on RB by repressing STAT3.
PubMed ID 29251322
Year 2018
Title miR-29a inhibits human retinoblastoma progression by targeting STAT3.
Drug-related ncRNA NO

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